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Barriers to treatment of hepatitis C in HIV/HCV coinfected adults in Brazil BJID
Mendes-Corrêa,Maria Cássia; Martins,LG; Ferreira,PA; Tenore,S; Leite,OH; Leite,AG; Cavalcante,AJW; Shimose,M; Silva,MH; Uip,DE; Abrão Ferreira,PR.
The objective of this study was to assess the prevalence of barriers to interferon treatment in a population of HIV/HCV coinfected patients. A cross-sectional study was conducted at two AIDS Outpatient Clinics in Brazil. The study included all HIV infected patients followed at these institutions from January 2005 to November 2007. Medical records of 2,024 HIV-infected patients were evaluated. The prevalence of anti-HCV positive patients among them was 16.7%. Medical records of HCV/HIV coinfected patients were analyzed. 189 patients with the following characteristics were included in our study: mean age 43 years; male gender 65%; former IDUs (52%); HCV genotype 1 (66.4%); HCV genotype 3 (30.5%); median CD4+ T cell count was 340 cells/mm³. Among 189 patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; HIV; Coinfected; Treatment.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300007
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Prevalence, risk factors and genotypes of hepatitis B infection among HIV-infected patients in the State of MS, Central Brazil BJID
Freitas,Solange Zacalusni; Soares,Caroline Cordeiro; Tanaka,Tayana Serpa Ortiz; Lindenberg,Andréa Siqueira Campos; Teles,Sheila Araújo; Torres,Marina Sawada; Mello,Francisco Campello Amaral; Mendes-Corrêa,Maria Cássia; Savassi-Ribas,Flávia; Motta-Castro,Ana Rita Coimbra.
Objectives:A cross-sectional study on prevalence of HBV and HDV infection, risk factors and genotype distribution of HBV infection was conducted among 848 HIV-infected patients in Mato Grosso do Sul, Central Brazil.Methods:Serum samples of 848 participants were tested for hepatitis B surface antigen (HBsAg), hepatitis B core antibody (anti-HBc) and hepatitis surface antibody (anti-HBs). HBsAg positive samples were tested for anti-HBc IgM, HBeAg, anti-HBe, anti-HCV, and total anti-HDV. HBsAg and anti-HBc positive were subjected to DNA extraction. Viral DNA was amplified by semi-nested PCR for the regions pre-S/S and then purified and genotyped/subgenotyped by direct sequencing. Student's t-test, chi-square test and Fisher's exact test were used to compare...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coinfection; HBV; HIV; Prevalence.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500473
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